Xcelience Expands Dry Granulation Expertise

Xcelience has expanded its solid oral dosage form development and manufacturing capabilities to include a Vector TFC-220 Roller Compactor in its GMP manufacturing area. The new equipment allows for faster transition from development in the experimental area to GMP production of clinical supplies. Dry granulation technology provides an option for clients with development challenges related to moisture sensitive APIs.

The company currently has a Vector TFC-Lab Micro Roller Compactor in the experimental area. The TFC-220 allows for scale-up to the GMP manufacturing area and expands the company’s processing capacity for dry granulation. The TFC-220 is capable of processing blends at a rate of up to 20 kg/hour.

“Taking a cross-functional approach to dry granulation ensures effective technical transfer and supports improved manufacturing outcomes,” said Ted Koontz, director of operations at Xcelience.